Embark on a new era of biopharmaceutical product development
It is within the lab where various phases of drug development occur in Life Sciences as new drugs and therapies are discovered and developed through extensive research. Labs lay the groundwork for quality control monitoring as promising drugs move through process development and pilot scale, followed by clinical and then commercial manufacturing. During the lab-scale research phase, a significant amount of analytical development takes place. Once a promising new drug has progressed through development and shows efficacy, process optimization begins, which is a crucial step in biopharma manufacturing. However, this early phase of the product lifecycle is quite challenging and cost intensive. Therefore, any efficiency improvements during this early phase can increase profitability down the line.
Process insights
Real-time process insights for faster market entry
As you begin to define and validate processes, methods, and parameters in the development of a new microorganism, the horizon teems with possibilities. However, time is of the essence. Swift action is imperative to bring your biological drug to market. Selecting the right cell lines and optimizing culture media profoundly impacts productivity, product quality, and safety. Understanding the interplay between upstream and downstream processes is also essential. Charting the right product development course from the start helps to ensure that a process will be resilient, efficient, and cost-effective.
Real-time, inline process analysis technologies, such as Endress+Hauser's Raman systems and Memosens digital sensor technology, open the door to true process understanding, optimization, and data-driven decision making. With 24/7 monitoring of process health, you know instantly when conditions veer off track, and can make quick proactive adjustments to avoid quality issues or product losses down the line. Ultimately, these process insights will drastically speed up development of the desired molecule, paving the way for faster market entry and optimal patient outcomes.
Tutorials
Learn about our inline measurement technologies
Want an overview of the measurement principles behind our cutting-edge inline measurement systems for biomanufacturing operations? Check out these pages for a quick tutorial.
A broad measurement portfolio optimized for upstream and downstream applications
From chemical composition to pH, DO, OD, concentration, and conductivity, we've got you covered.
Endress+Hauser offers a comprehensive bioprocessing portfolio. This arsenal includes cutting-edge Raman systems and Memosens technology for accurate process monitoring and tight control of all relevant parameters. By harnessing these world-class tools, you can bring new products to market with remarkable speed. From pH values to dissolved oxygen, conductivity, and chemical composition measurements, our bioprocessing analytic portfolio captures critical data and reveals valuable insights to keep your process up and running as your product takes shape. Download the eBook to learn how our inline measurement systems can supercharge your new product development efforts.
Select products for real-time chemical composition measurement
Endress+Hauser Raman spectroscopy systems, powered by Kaiser Raman technology, is the portfolio of choice in the Life Sciences industry to measure real-time chemical composition in upstream and downstream bioprocesses from lab to manufacturing. We offer a full suite of Raman instrumentation that works seamlessly with different bioreactor setups, including benchtop glass, plastic, and stainless steel. Here are a few highlighted offerings for reusable or single-use bioreactor set ups.
Select products for accurate monitoring of pH, DO, conductivity, and concentration
Endress+Hauser’s liquid analysis technology portfolio (including digital sensors, transmitters, photometers, and assemblies) delivers precise and consistent measured values of important process parameters such as pH, dissolved oxygen, conductivity, and more. Featuring Heartbeat Technology with predictive maintenance capabilities, our digital analysis suite offers long sensor life and full scalability from the laboratory straight to pilot and process. Here are just a few highlighted products to explore.
There's a lot to consider when evaluating inline measurement techniques to support your product development effortsl. It's important to consider key factors like breadth of portfolio, quality of materials, flexibility of integration capabilities, and global service and support. Here are some answers to common questions you may have pertaining to how our Raman and liquid analysis digital technologies can support your product development needs.
Why do Life Sciences companies choose Endress+Hauser?
Quite simply, our track record speaks volumes. Check out this infographic to see why Endress+Hauser has earned the trust of leading biopharmaceutical leaders all around the world.
Many PAT and process development scientists today are seeking new biotech solutions to scale seamlessly from lab to production and optimize current processes. Learn how Endress+Hauser's broad bioprocessing portfolio can help achieve these key business objectives.
Scale smoothly up to production
Build a scalable process that is easily transferable to manufacturing using different bioreactor setups.
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